BLADDERCELL
BladderCell is a startup within the Leonhardt Ventures Cal-X Stars Business Accelerator and Leonhardt’s Launchpads Utah focused on bladder regeneration.
The company utilizes bioelectric stimulation to control release of specific proteins on demand for specific regenerative purposes in sequence:
1. SDF-1 (stem cell homing factor – recruits a persons own stem cells to stimulated tissues).
2. VEGF (for new blood vessel growth).
3 IGF-1 (for DNA repair at the nucleus level).
4. Follistatin (for muscle and tissue regeneration).
5. RANKL (for demineralization and tissue loosening when needed).
6. Hepatocyte Growth Factor (tissue regeneration)
7. eNOS (for dilating blood vessels for increasing flow).
8. Tropoelastin (increases elasticity of any tissues such as skin, arteries, aorta, heart and promotes healing of wounds).
9. Activin A + B
In extreme cases we combine our regeneration microstimulator with an implantable, programmable, re-fillable stem cell/growth factor micro pump.
In cases of bladder cancer we have special signals to stop tumor cell division and blood supply followed by the above regeneration protocol.
BladderCell
Leonhardt’s Launchpads Utah
489 E, 400 South, Unit 116
Salt Lake City, UT 84111
email: hleonhardt@aol.com
Contact: Howard J. Leonhardt
Related Scientific Articles
SDF-1
Search Results
[PDF]
272 involvement of sdf-1 in recruitment of alpha smooth muscle actin
www.ics.org/Abstracts/Publish/106/000272.pdf
International Continence Society
Trials on the urinary bladder regeneration by acellular grafts have not always … stromal cell-derived factor 1 (SDF–1) in bladder muscle regeneration in in vitro …
[PDF]
www.ics.org/Abstracts/Publish/…/000272_poster.pdf
International Continence Society
by M Imamura – Related articles
SDF–1 could be a pivotal signal for inducing the inflammatory phase of bladder regeneration through migration of myofibroblast-like cells into the graft.
In situ tissue regeneration through host stem cell recruitment
www.nature.com/emm/journal/v45/n11/full/emm2013118a.html
Nature
by IK Ko – 2013 – Cited by 40 – Related articles
Nov 15, 2013 – In situ tissue regeneration utilizes the body’s own regenerating capacity by ….. In an attempt to protect SDF–1α effects from endogenous inhibitors, ….. Bladder acellular matrix graft in rats: its neurophysiologic properties and …
HGF
In vitro comparative evaluation of recombinant growth factors for tissue …
www.ncbi.nlm.nih.gov/…/24095026
National Center for Biotechnology Information
by B Yang – 2014 – Cited by 12 – Related articles
Aug 15, 2013 – In vitro comparative evaluation of recombinant growth factors for tissue … the effects of various recombinant growth factors on bladder regeneration and … hepatocyte growth factor (HGF), and transforming growth factor beta 1 …
IGF-1
Engineered insulin-like growth factor-1 for improved smooth … – NCBI
www.ncbi.nlm.nih.gov/…/22014943
National Center for Biotechnology Information
by KM Lorentz – 2012 – Cited by 18 – Related articles
Oct 19, 2011 – Insulin-like growth factor-1 (IGF–1) has been shown to induce potent … Recombinant Proteins/metaboli
Functional rat bladder regeneration through xenotransplantation of the …
onlinelibrary.wiley.com › … › Vol 81 Issue 4 › Abstract
John Wiley & Sons
by HJ PIECHOTA – 1998 – Cited by 73 – Related articles
Dec 25, 2001 – In addition, the contractility of the BAMG-regenerated bladders was examined with in vitro electrical and pharmacological stimulation …New Drugs Will Ignite Bladder Cancer Treatment …
https://healthcare.globaldata.com/…/trio-of-exciting-new-drugs-will-ignite-bladder-ca…
Jan 14, 2016 – The bladder cancer treatment market is set to boom from an estimated … The company’s latest report* states that the growth, which will occur across the … Heart Failure Market to
Electrical stimulation to vagina muscle cells and rabbit bladder muscle …
www.researchgate.net/…/261059642_Electrical_stimulation_to_vagina_mu… ResearchGate
Publication » Electrical stimulation to vagina muscle cells and rabbit bladder muscle … Article:Electrical stimulation promotes motoneuron regeneration without …
Role of electrical stimulation for rehabilitation and regeneration after …
www.ncbi.nlm.nih.gov/…/PMC25274…
National Center for Biotechnology Information
by S Hamid – 2008 – Cited by 113 – Related articles
Aug 2, 2008 – Electrical stimulation in the form of functional electrical stimulation (FES) can …bladder or bowel functions by applying a controlled electrical …
Electrical Stimulation for Urinary Incontinence in Women: A Systematic …
www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382013000400454
… severity of coronary artery disease and severity of erectile dysfunction? author index … Intravaginalelectrical stimulation showed effectiveness in treating urge urinary ….. (ICS) joint report on the terminology for female pelvic floor dysfunction. …. 6690 / 612, Centro Clínico, Jardim Botânico, Porto Alegre, 90610-001, Brazil, …
Human amniotic fluid stem cell injection therapy for urethral sphincter …
Aug 21, 2012 – Recently, human amniotic fluid stem cells (hAFSCs) have been proposed as an ideal … Nerve regeneration and neuromuscular junction formation of injected …… tracking of human amniotic fluid stem cells in the mouse heart.
Can electric pants help stop embarrassing leaks? Device uses …
Sep 28, 2015 – Device uses electrical stimulation to strengthen pelvic floor muscles … I used to love running and doing yoga, but it became impossible. ‘I never …