CancerCell is a startup within the Leonhardt’s Launchpads innovation accelerator operated by Cal-X Stars Business Accelerator, Inc. focused on bioelectric signals to stop tumor growth by halting cell division and starving blood supply to the tumor.
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Electricity and Stem Cells: Old Signal for New Therapies
All these actions are the detectable expression of cell’s ability to quickly and … the induction of differentiation of cancer stem cells, are just some applications of this … bioelectrical signals that control regeneration promoting protein expression
It’s Electric: Biologists Seek to Crack Cell’s Bioelectric Code – Scientific …
Mar 27, 2013 – Researchers have found that cells’ bioelectrical communication steers … manipulating cellular signaling could be used to stave off cancer or even … which have the ability to grow into other cell types as well as tumor cells
Tumor Initiation; Invasion; Ricci Flow; Bioelectric Control; Receptor …
Oct 17, 2016 – Tufts biologists show bioelectrical signals control tumors arising from cancer-
Membrane potential and cancer progression – NCBI – NIH
Jul 17, 2013 – It is well-established that cancer cells possess distinct bioelectrical properties. ….. Moreover, IHERG increases tumor cell proliferation (Bianchi et al., ….. DNA and protein syntheses and glial fibrillary acidic protein expression in .
Cancer, Bioelectrical Signals and the Microbiome Connected | Tufts Now
now.tufts.edu/news-releases/cancer-bioelectrical-signals-and-microbiome-connected
May 27, 2014 – Tufts biologists show bioelectrical signals control tumors arising from … the incidence of tumors arising from cancer-causing genes and that this
Bioelectric Signals Can Be Used to Detect Early Cancer | Tufts Now
Feb 1, 2013 – Changing bioelectric signals a key to halting tumor growth … Chernet and Levininvestigated the bioelectric properties of cells that develop into …
Alternating electric fields arrest cell proliferation in animal tumor …
www.pnas.org/content/104/24/10152.long
Jun 12, 2007 – In view of the relatively slow kinetics of the bioelectrical responses,
FDA approves the treatment of brain tumors with electrical fields
Feb 13, 2012 – NovoTTF is first ever FDA approved cancer treatment for patients as an alternative … treatment by Novocure uses “Tumor Treating Fields” (NovoTTF) to treat … The results from a 237-patient trial indicated that NovoTTF treated …
Study of effect of microsecond pulsed electric fields on threshold area …
Microsecond pulse electric field (μsPEF) application development … the μsPEF on the threshold area (TA) of human cervical cancer cells (HeLa) membrane. … While the cultured skin cells are placed in 9 mm-gap EP electrode chamber for …. Faculty of Bioscience and Bioengineering, Universiti Teknologi Malaysia, Malaysia …
A new pulsed electric field therapy for melanoma disrupts the tumor’s …
Richard Nuccitelli at Pulse Biosciences Inc. … We have discovered a new, ultrafast therapy for treatingskin cancer that is extremely … In a later study[402], it was shown that after nsPEF ablation (300–600pulses, 300 ns, 40–50 ….. is a basic and most thoroughly studied bioelectric effect caused by pulsedelectric fields.
Nano-Pulse Stimulation is a physical modality that can trigger …
Apr 18, 2017 – Journal for ImmunoTherapy of Cancer20175:32 …… all work for Pulse Biosciences andPulse built the pulse generator used in this study.
Intense picosecond pulsed electric fields inhibit proliferation and …
this study, we exposed HeLa cells to a psPEF with a variety of … Cervical cancer is the most common malignant tumor of the … clinical therapies, including the treatment of head, neck, skin, …. (FACS) Vantage SE flow cytometer system (BD Biosciences, ….. Bioelectric studies with subnanosecond pulsedelectric fields.
Bioelectric controls of cell proliferation: Ion channels, membrane …
May 6, 2009 – … Cycle 8:21, 3527-3536; November 1, 2009; © 2009 Landes Bioscience … and the cell cycle, this fascinating bioelectric control mechanism …. results have been supported in studies of human prostate cancer …. electric pulses on a millisecond timeframe, is widely used in cell … and examined in intact skin.
Electricity and Stem Cells – Parent’s Guide to Cord Blood
Oct 13, 2016 – Endogenous bioelectric currents are involved in normal tissue … halt blood supply, as may be needed in the case of starving cancer tumors.
A new pulsed electric field therapy for melanoma disrupts the tumor’s …
We have discovered a new, ultrafast therapy for treating skin cancer that is extremely … This reducedblood flow to the tumor and activation of apoptosis pathways cause the tumor … is that (i) they are fastenough to penetrate into the cell and all organelles; and (ii) they are ….. Bioelectric effects of intense nanosecond pulses.
Starving Tumors of their Blood Supply | NutritionFacts.org
https://nutritionfacts.org › Dr. Greger’s Medical Nutrition Blog
Mar 25, 2014 – About a third of common cancers may be prevented by eating a healthy, … Another waytumors commandeer a blood supply is by diabolically …
Potential Tactics for Defeating Cancer — A Toolkit in 1,000 Words …
Jan 28, 2014 – But if cancer cells get constant blood and glucose? … to “anti-angiogenesis therapy”: in plain English, how to starve cancers of blood. …. group examining role of ketogenic diet and hyperbaric oxygen on a very aggressive tumor model ….. Contrary to inhibiting the blood supply to cancers espoused by Dr. Li.
Endogenous Voltage Potentials and the Microenvironment: Bioelectric …
Oct 8, 2013 – Cancer can be seen as an error of geometry, because tumor cells grow, migrate, … Moreover, resting potential established by ion channel and pump proteins is … These voltage gradients regulate the expression of genes like …
Healing Cancer With Electricity: ECT • BET • PBE • Galvanotherapy for …
www.healingcancernaturally.com/greatesthits4.html
… Therapy (ECT), Bio-Electric Therapy (BET), Percutaneous Bio-Electrotherapy …. phagocytic cells (stimulated where required via additional immunotherapy) …
Bioelectric Applications for Treatment of Melanoma – NCBI – NIH
Sep 27, 2010 – Two new cancer therapies apply bioelectric principles. … Addition of systemicimmunotherapy with IL-2 and/or INFά to these regiments resulted …
Tumor Bioelectric Potential and its Possible Exploitation for Tumor …
www.tandfonline.com/doi/pdf/10.3109/15368379009119801
The short-term imposition of tumor bioelectric potential (voltage difference imposed by the therapy) depended on the bioelectric potential prior to the therapy in …
Altering bioelectricity on inhibition of human breast cancer cells (PDF …
Full-text (PDF) | Altering bioelectricity on inhibition of human breast cancer cells. … levels of protein expression of caspase-3 were increased. by verapamil in a …
Bioelectric cancer hack – ScienceDirect
www.sciencedirect.com/science/article/pii/S0262407916304419 ScienceDirect
by J Hamzelou – 2016
Mar 19, 2016 – It’s not just our brains and hearts – almost every cell has an electrical charge, and hacking it might be a way to treat cancer. Researchers have …
Electronic Medicine Fights Disease – Scientific American
www.scientificamerican.com/…/electronic-medicine-fights-disease/
Scientific American
Stimulation of the nervous system could replace drugs for inflammatory and autoimmune conditions.
An Electrical Off-Switch for Disease [Video] – Scientific American
www.scientificamerican.com/…/bioelectronic-an-electrical-off-swit…
Scientific American
Mar 1, 2015 – Stimulator devices can tweak nervous system activity to turn down inflammation or treatother effects of disease.
FDA approves the treatment of brain tumors with electrical fields
newatlas.com/treatment-of-brain-tumors-with-electrical-fields/21433/
Feb 13, 2012 – The promising new non-invasive treatment by Novocure uses “Tumor Treating Fields” (NovoTTF) to treat cancerous growths and is now available for adult patients with recurring braintumors (recurrent glioblastoma or GBM). The treatment delivers electric fields to a patient utilizing …
Cancer, bioelectrical signals and the microbiom… – Scoop.it
www.scoop.it/…tumor–cancer…/cancer–bioelectrical-signals-and-the-microbiome-con…
May 28, 2014 – Project Virtual Tumor Cancer in silico and Alternative Cancer Therapies. … Novocure initially received U.S. FDA approval for Optune in 2011 for .
Bioelectric Signals Can Be Used to Detect Early Cancer | Tufts Now
now.tufts.edu/news…/bioelectric-signals-used-detect-early-cancer
Tufts University
Feb 1, 2013 – Bioelectric Signals Can Be Used to Detect Early Cancer … with embryos that received the oncogene but no hyperpolarizing channel treatment.
Bioelectric Applications for Treatment of Melanoma
www.ncbi.nlm.nih.gov/…/PMC38373…
National Center for Biotechnology Information
by SJ Beebe – 2010 – Cited by 11 – Related articles
Sep 27, 2010 – Two new cancer therapies apply bioelectric principles. These methods target tumor structures locally and function by applying millisecond …
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Chen XH, Zhang XM, Yin SY, Zheng SS.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2015 Jan;44(1):108-11. Chinese. No abstract available.
PMID: 25851985
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Chernet BT, Fields C, Levin M.
Front Physiol. 2015 Jan 19;5:519. doi: 10.3389/fphys.2014.00519. eCollection 2014.
PMID: 25646081 Free PMC Article
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Levin M.
Mol Biol Cell. 2014 Dec 1;25(24):3835-50. doi: 10.1091/mbc.E13-12-0708.
PMID: 25425556 Free PMC Article
The Bioelectrical Interplay Between Inflammation and Cancer. | UA …
www.undergraduatelibrary.org/…/bioelectrical-interplay-between-inflammation-and-c…
The Bioelectrical Interplay Between Inflammation and Cancer. It is believed that fundamentally cancer is caused by genetic mutations in an individual cell which …
Safer, more convenient pump to treat pediatric brain cancer | NSF …
CancerCell News
Leonhardt Ventures to Enter Into Worldwide Strategic Collaboration …
Feb 22, 2017 – CancerCell, a Leonhardt Ventures’ startup – see video …. Leonhardt Ventures and CerebraCell File Patent Application for Treating Cancer …
Leonhardt Startup CancerCell Expands IP Estate for … – BioSpace
Oct 20, 2017 – Leonhardt Startup CancerCell Expands IP Estate for Bioelectric Treatment of Cancer Tumors – read this article along with other careers …