CerebraCell

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cerebraCerebraCell is focused on brain regeneration utilizing patented microcurrent signals that home stem cells to the brain and cause new blood vessels to grow.  For advanced severe cases we add stem cell and growth factor injections and for extremely advanced cases we implant a re-fillable, programmable micro pump regeneration stimulator.

Product Description = Cerebracell is designed to stimulate true neurogenesis, the formation and nurturing of new neuron cells, to regenerate damaged or diseased brain tissue = true brain regeneration.  We do this by bioelectric stimulation controlled release of more than 10 essential brain regeneration promotion cytokines.  Our most important controlled cytokine release is SDF-1 which is a stem cell homing factor which recruits stem cells from a patient’s own bone marrow, fat and circulating blood to the stimulated brain tissue areas.  We have another signal of opposite polarity for controlling the differentiation of those recruited stem cells into healthy functioning brain tissue.  We also stimulate the release of IGF-1 for DNA level repair, HGF, EGF, Activin A+B, eNOS, VEGF, Follistatin and Tropoelastin all of which contribute to regeneration.  eNOS, HGF and VEGF help improve blood supply to the treated area.  For severe brain damage recovery and difficult disease cases we add our programmable micro infusion pump which is filled daily or weekly with our proprietary CCA-15 and CCR-15 fifteen component angiogenic and regeneration compositions comprised of a variety of cell types, growth factors, nutrient hydrogel, exosomes, Micro RNAs, brain matrix and other neurogenesis promoting molecules including harmine and tetrahydroharmine alkaloids and inflammation control agents We believe that our combination bioelectric regeneration stimulator, micro infusion pump and proprietary 15 component angiogenic + regeneration compositions have the potential to do a better job of helping people recover from brain injuries or brain related diseases than any other therapy brought forward before.  We are on a path to implement well designed clinical trials to prove this out.

For brain tumor cancer patients we have patent pending specially tuned bioelectric signals designed to stop cell division and blood supply to the tumors. 

CerebraCell is targeting these disease states and conditions:

  • Cerebral stroke recovery.
  • Concussion recovery.
  • Injury related brain damage.
  • Brain cancer recovery.
  • Parkinson’s.
  • Alzheimer’s and dementia.
  • Cerebral aneurysm repair.
  • Depression.
  • Brain memory recovery and enhancement.
  • Brain function enhancement.

Corporate Affairs:

CerebraCell operates as a subsidiary of Leonhardt Ventures (Leonhardt Vineyards LLC DBA Leonhardt Ventures).

Leonhardt Ventures

1531 6th Street, Unit 401

Santa Moncia, CA  90401

Office DIRECT 310 310 2534

Executive Chairman and CEO:  Howard J. Leonhardt – hleonhardt@aol.com

President and CSO:  Dr. King Liu – YKingLiu@uncm.edu,

Director of Marketing:  Brian Hardy – brian@fizzpopmedia.com

CerebraCell is duly incubating in the Cal-X Stars Business Accelerator, Inc. in collaboration with LABioHub and LABioMed in Santa Monica, California www.calxstars.com and Leonhardt’s Launchpads www.leonhardtslaunchpads.com at the University of Northern California Science and Technology Center in Rohnert Park, CA – http://www.uncm.edu/STIC.php  – University of Northern California, 1300 Valley House Dr, Suite # 100-27

Rohnert Park, CA 94928, (707) 664-6365

Investments in CerebraCell may only be made by verified accredited investors via investing in Cal-X Stars Business Accelerator, Inc. at this time –
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IGF-1

IGF-1 Controlled Release by Bioelectric Stimulation Provisional Patent …

mysocialgoodnews.com/igf1-controlled-release-bioelectric-stimulation-provisional-p…

Apr 2, 2016 – It has been demonstrated to be especially useful in brain regeneration. Some people have referred to IGF1 as the Fountain of Youth. We are ..

IGF-1 Reverses Aging and Heals damaged brain cells – Peptides

researchpeptides.com › Forum › Peptide Research › General Industry Discussion

Nov 12, 2015 – Growth Hormone Production and IGF1 The production of growth hormone is … HG has manifested the regeneration of damaged brain tissue.

effect of locally delivered igf-1 on nerve regeneration during … – NCBI

www.ncbi.nlm.nih.gov/…/PMC30457…

National Center for Biotechnology Information

by PJ Apel – ‎2010 – ‎Cited by 53 – ‎Related articles

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Role and Importance of IGF-1 in Traumatic Brain Injuries

www.hindawi.com/journals/bmri/2015/736104/

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Insulin-like growth factor II stimulates motor nerve regeneration

www.pnas.org/…/11716.full.p…

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factor H (IGF-ll) can stimulate motor nerve regeneration was … known as insulin-like growth factor II. (IGF-II) (10, 11) is one candidate diffusible substance. Brain.

Insulin-like growth factor (IGF-I) as a stimulator of regeneration in the …

https://www.researchgate.net/…/20436630_Insulin-like_growth_factor_IG ResearchGate

Brain Res 485: 102-108 on ResearchGate, the professional network for … The results suggest that IGF1 affects regeneration by local stimulation of the growing …

The Insulin-Like Growth Factor 1 Receptor Is Essential for Axonal …

journals.plos.org/plosone/article?id=10.1371/journal.pone.0054462

by S Dupraz – ‎2013 – ‎Cited by 19 – ‎Related articles

Jan 18, 2013 – Axonal regeneration is an essential condition to re-establish functional neuronal … kinase (PI3K) signaling pathway, upon stimulation with IGF1. … The expression of IGF-1R is developmentally regulated in brain, reaching …

Hippocampal IGF-1 expression, neurogenesis and slowed aging …

link.springer.com/article/10.1007/s11357-006-9009-5 Springer Science+Business Media

by LY Sun – ‎2006 – ‎Cited by 13 – ‎Related articles

The Ames dwarf mouse is a murine model of circulating GH and IGF1 … 2002), whereas transgenic mice with ectopic brain expression of IGFBP-1, …. oligodendrocytes from injury and/or in promoting their regeneration following injury.

Postischemic IGF-1 Gene Transfer Promotes Neurovascular …

jcb.sagepub.com/content/29/9/1528.full

by W Zhu – ‎2009 – ‎Cited by 40 – ‎Related articles

Postischemic IGF1 Gene Transfer Promotes Neurovascular Regeneration after … There is great enthusiasm to repair the brain after stroke injury because .

SDF-1 

Potential of Neural Stem Cell-Based Therapy for Parkinson’s Disease

www.hindawi.com/journals/pd/2015/571475/

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Development of stem cell-based therapy for Parkinson’s disease …

translationalneurodegeneration.biomedcentral.com/articles/10…/s40035-015-0039-8

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[PDF]

Use of Genetically Modified Mesenchymal Stem Cells to Treat …

www.mdpi.com/1422-0067/15/2/1719/pdf

MDPI

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Jan 23, 2014 – Abstract: The transplantation of mesenchymal stem cells (MSCs) for treating … Keywords: mesenchymal stem cells; genetic engineering; Parkinson’s; … factor-1 (SDF1), which is expressed in areas of inflammation in the brain …

Role of the SDF-1-CXCR4 axis in stem cell-based therapies for …

https://www.researchgate.net/…/41406917_Role_of_the_SDF1-CXCR4_a… ResearchGate

Role of the SDF1-CXCR4 axis in stem cell-based therapies for ischemic … Neuron Development In Vivo to Improve Stem Cell Therapy in Parkinson’s Disease.

The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12 …

bmcneurosci.biomedcentral.com/articles/10.1186/1471-2202-6-63

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In addition to targeting hematopoietic cells, the SDF1/CXCR4 system is also known to play a critical role in embryonic brain development and adult injury repair …

SDF-1:CXCR4 Axis Is Fundamental for Tissue Preservation and Repair

www.ncbi.nlm.nih.gov/…/PMC29667…

National Center for Biotechnology Information

by MS Penn – ‎2010 – ‎Cited by 23 – ‎Related articles

Aug 13, 2010 – Further demonstrating the importance of the SDF1 in tissue repair, … heart and brain, up-regulation of the SDF1:CXCR4 axis is a fundamental …

Neural Regeneration – Page 226 – Google Books Result

https://books.google.com/books?isbn=0128018348

Kwok-Fai So, ‎Xiao-Ming Xu – 2015 – ‎Science

KLF family members regulate intrinsic axon regeneration ability. … Brain Res Mol Brain Res 1994;24:43–54. … [232] Yin Y, Li Y, Cen L-P, Gilbert H-Y, Cui Q, Benowitz L. Stromal cellderived factor-1 (SDF1) contributes to inflammation-induced …

New Insight Into How The Brain Regenerates After Stroke …

https://www.sciencedaily.com/releases/2006/12/061223092924.htm

Science Daily

Dec 23, 2006 – His lab studies the mechanisms of brain repair and the recovery of function … “TheSDF1 and Ang1 proteins are what link the two processes of …

Regeneration of Neuronal Cells following Cerebral Injury – FullText …

https://www.karger.com/Article/FullText/346407

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Jul 8, 2013 – Department of Neurosurgery and Brain Repair, University of South Florida … When SDF1is active, HSCs cross the endothelial blood-BM barrier and … factor markedly improved stroke recovery in the animal models [16].

A Neurovascular Niche for Neurogenesis after Stroke

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Dec 13, 2006 – Furthermore, SDF1 and Ang1 promote post-stroke neuroblast … These experiments define a novel brain environment for neuronal regeneration after stroke and … and neurogenesis during functional recovery from brain injury.

UCLA Study Identifies Cellular Cues for Stroke Recovery | UCLA

newsroom.ucla.edu/…/UCLA-Study-Identifies-C…

University of California, Los Angeles

Jan 4, 2007 – When a stroke strikes, the supply of blood to the part of the brain … cues are necessary for this process of regeneration andmigration to take place. … stromal-derived factor 1 (SDF1) and angiopoietin 1(Ang1) — given off by …

Frontiers | Neurorestorative Therapy for Stroke | Frontiers in Human …

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Stroke is one of the leading causes of mortality, long-term disability, and …. the adult CNS is critical tobrain repair processes after stroke (Hou et al., 2008). …. Neuropilin-1 (Nrp-1), NO, SDF1, and VEGF may maximize recovery (Madri, 2009).

HGF

Hepatocyte growth factor, a versatile signal for developing neurons …

www.nature.com › Journal home › Archive › Table of Contents › Review

Nature

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Hepatocyte growth factor (HGF, also known as scatter factor) is one example of such a … It was later found to be involved in organ regeneration, angiogenesis and tumor … Both HGF and Met are expressed during brain development, and their …

Therapeutic potential of hepatocyte growth factor against cerebral …

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Dec 15, 2014 – Hepatocyte growth factor (HGF) is a potent pleiotropic cytokine that is involved in … in a variety of cells, and tissue regeneration in several organs (7–9). … be one of the most potent growth factors for treating brain ischemia.

Brain repair: cell therapy in stroke – NCBI – National Institutes of Health

www.ncbi.nlm.nih.gov/…/PMC39371…

National Center for Biotechnology Information

by D Kalladka – ‎2014 – ‎Cited by 32 – ‎Related articles

Feb 21, 2014 – In the animal models of stroke, both mesenchymal stem cells (MSCs) and neural stem cells (NSCs) improve functional recovery, and MSCs …. experimentally by extrinsic growth factors, likehepatocyte growth factor,22 and …

Angiogenesis, neurogenesis and brain recovery of function following …

www.ncbi.nlm.nih.gov/…/PMC28361…

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Traumatic brain injury and stroke are major causes of mortality and morbidity worldwide. … the repairand regeneration of injured brain tissue and functional recovery. ….. MSCs transferred with ex vivohepatocyte growth factor gene are more …

Therapeutic potential of hepatocyte growth factor against cerebral …

https://www.spandidos-publications.com/etm/9/2/283

by W Zeng – ‎2015 – ‎Cited by 1 – ‎Related articles

Dec 15, 2014 – Hepatocyte growth factor (HGF) is a potent pleiotropic cytokine that is involved in cell … in a variety of cells, and tissue regeneration in several organs (7–9). … brain tissue of patients who had survived acute ischemic stroke for up to ….. XF: VEGF promotes angiogenesis and functionalrecovery in stroke rats.

Acute hepatocyte growth factor treatment induces long-term …

https://www.researchgate.net/…/49647093_Acute_hepatocyte_growth_fact… ResearchGate

Hepatocyte growth factor (HGF) is an interesting candidate for acute stroke … (5 μg) after a 45-minutestroke, with regard to brain injury and neurologic recovery. …… in biological procedures relating to development and regeneration [3] [4].

Regeneration of Neuronal Cells following Cerebral Injury – FullText …

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Jul 8, 2013 – Naritomi H, Krieger DW (eds): Clinical Recovery from CNS Damage. … Department of Neurosurgery and Brain Repair, University of South Florida …. as: hepatocyte growth factor (HGF), vascular endothelial growth factor, … For example, early increases (1 h after stroke) could increase blood-brain barrier …

Hepatocyte growth factor mediates mesenchymal stem cell-induced …

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Growth Factors Released from Gelatin Hydrogel Microspheres …

www.hindawi.com/journals/sci/2012/915160/

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Aug 9, 2012 – Hepatocyte growth factor (HGF)-containing microspheres increased the … release of growth factors holds promise for the clinical regeneration of … new neurons to the injured brain afterstroke in a mouse model. … After surgery, the animals were left on a heat mat and constantly monitored until recovery.

Follistatin

Tissue absence initiates regeneration through Follistatin-mediated …

https://www.researchgate.net/…/256614967_Tissue_absence_initiates_rege ResearchGate

Smed-follistatin inhibits Smed-Activin proteins to trigger regeneration specifically following ….. and did not regenerate a brain as assayed with an RNA probe for …

Follistatin-Like 1 Attenuates Apoptosis via Disco-Interacting … – Stroke

stroke.ahajournals.org/content/45/10/3048.full Stroke

by X Liang – ‎2014 – ‎Cited by 3 – ‎Related articles

Aug 19, 2014 – Recombinant FSTL1 reduced brain infarction and improved … The incision was closed with sutures, and the rat was allowed to recover.

[Expression of follistatin, activin A and BMP-4 in rats with … – JoVE

www.jove.com/…/expression-follistatin-activin-bm…

Journal of Visualized Experiments

Oct 25, 2014 – Here we describe a protocol that has been optimized to recover these discs … At present, two major types of ischemic stroke models have been …

Activin 

Scientists identify main component of brain repair after stroke …

https://www.nih.gov/…/scientists-identify-main-componen

National Institutes of Health

Oct 27, 2015 – Scientists identify main component of brain repair after stroke … “We found thatregeneration is a unique program in the brain that occurs after …

Biologists have found a gene that controls brain repair | ExtremeTech

www.extremetech.com › Extreme

ExtremeTech

Oct 29, 2015 – Control of a single gene can stimulate partial regeneration after a damaging stroke, in both live mice and cultured human …

[PDF]

ACTIVIN A REDUCES BRAIN INJURY AFTER STROKE by SHIBANI S …

https://etd.ohiolink.edu/rws_etd/document/get/case1228061151/inline

by SS Mukerji – ‎2009 – ‎Cited by 1 – ‎Related articles

Oct 17, 2008 – administration of activin A prior to stroke onset protected against ….. information on circuit reorganization and repair mechanisms …… growth and tubulogenic effects on endothelial cells necessary for hepatic regeneration.

Neuroregenerative strategies in the brain: emerging significance of …

www.nrcresearchpress.com/doi/full/10.1139/O08-116?mobileUi=0

Sep 24, 2008 – aNeurogenesis and Brain Repair Group, Neurobiology Program, …. andneuroregeneration in animal models of brain injury and stroke (Chang et al. 2003 … BMP receptor II (BMPRII), activin receptor IIA (ActRIIA), and activin …

The roles of activins in repair processes of the skin and the brain.

www.ncbi.nlm.nih.gov/…/11451588 National Center for Biotechnology Information

by B Munz – ‎2001 – ‎Cited by 50 – ‎Related articles

Mol Cell Endocrinol. 2001 Jun 30;180(1-2):169-77. The roles of activins in repair processes of the skin and the brain. Munz B(1), Tretter YP, Hertel M, Engelhardt …

Activin: a novel player in tissue repair processes. – NCBI

www.ncbi.nlm.nih.gov/pubmed/9987674 National Center for Biotechnology Information

by G Hübner – ‎1999 – ‎Cited by 58 – ‎Related articles

Recent studies have demonstrated a strong expression of activin in repair … the skin, the lung, the intestine, the cardiovascular system, and even the brain.

Activin plays a key role in the maintenance of long-term memory and …

learnmem.cshlp.org/content/17/4/176.full

by H Ageta – ‎2010 – ‎Cited by 25 – ‎Related articles

Thus, the level of activin in the brain during the retrieval phase plays a key role in the … 1A), which eliminates the possibility that neuronal damage occurred.

VEGF 

Roles for VEGF in Brain Repair

https://expert.gwu.edu/display/doc-0d26a7a817d19069ccdf1018278813a1

Home · Organizations. Roles for VEGF in Brain Repair Conference Paper uri icon. Overview. authors. Janette M Krum. publication date. 2004. presented at event.

Role of vascular endothelial growth factor in neuronal DNA damage …

www.ncbi.nlm.nih.gov/…/12271463

National Center for Biotechnology Information

by ZJ Yang – ‎2002 – ‎Cited by 84 – ‎Related articles

Oct 15, 2002 – … growth factor in neuronal DNA damage and repair in rat brain following a … Western blot analysis further illustrated that VEGF induction was …

JCI – VEGF: a critical player in neurodegeneration

www.jci.org/articles/view/20682

Journal of Clinical Investigation

by E Storkebaum – ‎2004 – ‎Cited by 178 – ‎Related articles

VEGF can also have favorable effects on the recovery of an ischemic brain insult. …. DNA damage andrepair in rat brain following a transient cerebral ischemia.

Neurotrophic Effects of Vascular Endothelial Growth Factor on …

www.jneurosci.org/content/23/35/11036.full.pdf

The Journal of Neuroscience

by JM Rosenstein – ‎2003 – ‎Cited by 191 – ‎Related articles

for the first time, that VEGF is directly neurotrophic to CNS neurons in culture. …… revascularization and astroglial proliferation: roles for VEGF in brain repair.

VEGF overexpression induces post-ischaemic neuroprotection … – Brain

brain.oxfordjournals.org/content/128/1/52

Brain

by Y Wang – ‎2005 – ‎Cited by 219 – ‎Related articles

Oct 27, 2004 – In fact, early post-ischaemic systemic delivery of VEGF increased blood–brain barrier (BBB) leakage and tissue damage after stroke, while …

Research progress of VEGF and brain injury repair mechanism

wprim.whocc.org.cn/local/detail.jsp?channelid=75002&searchword…

Vernacular Title: VEGF与颅脑损伤修复机制的研究进展. Author: Keywo

Electrical Stimulation 

Stimulating brain with electricity ‘boosts stroke recovery’ – BBC News

www.bbc.com/news/health-35821286

BBC

Mar 17, 2016 – Stimulating the brain with electrical current can help improve recovery after a stroke, research from the University of Oxford suggests.

“Micro-Current Biotech” Therapy for Stroke Rehabilitation from WWC …

https://www.linkedin.com/…/micro-current-biotech-therapy-strokerehabilita

LinkedIn

Dec 15, 2015 – Micro-Current Biotech” Therapy for Stroke Rehabilitation from WWC Probiotics, …TENS and later on MENS are used to take away pain of Diabetic … talk about strategy as if it’s some kind of high-brain scientific methodology.

Post-Stroke Treatment with Microcurrent and Acupuncture – YouTube

 5:17

https://www.youtube.com/watch?v=pL3C4GkI3Ho

May 29, 2013 – Uploaded by MicroLightVideos

Post-Stroke Treatment with Microcurrent and Acupuncture … of microcurrenttherapy, Microlight therapy …

Electrical brain stimulation could support stroke recovery: Hand and …

https://www.sciencedaily.com/releases/2016/03/160316151108.htm

Science Daily

Mar 16, 2016 – Applying an electric current to the brain can help recovery from stroke, Oxford University researchers have found. A team from Oxford’s Nuffield …

Electrical Stimulation Elicits Neural Stem Cells Activation: New … – NCBI

www.ncbi.nlm.nih.gov/…/PMC46102…

National Center for Biotechnology Information

by Y Huang – ‎2015 – ‎Cited by 1 – ‎Related articles

Oct 19, 2015 – Keywords: electrical stimulation, neural stem cells, activation, … that endogenous NSCs can be a potential therapy for brain tissue repair.

Edmonton Neurotherapy: Non-Invasive Brain Stimulation …

www.edmontonneurotherapy.com/brain_stimulation_therapies.html

Information on non-invasive brain stimulation/neuromodulation technologies … for medical devices using microcurrent levels of electrical stimulation across the ….. within stroke rehabilitationprograms to enhance motor function re-learning.

Directing migration of human stem cells with electric fields …

https://www.cirm.ca.gov/…/directing-mi

California Institute for Regenerative Medicine

We will combine the electric stimulation with other treatment to establish a potent and … We aim to guide human stem cells to repair diseased or damaged tissues. … electric fields in the brain, which may guide migration of neural stem cells.

Electrical Stimulation of the Brain Boosts Birth of New Cells

www.sfn.org/…/ElectricalStimulation-of-the-Brain-Boosts-B…

Society for Neuroscience

Animal study suggests deep brain stimulation improves memory … and Science, an expert on stem cells and brain repair who was unaffiliated with the study.

Developing stem cell-based therapies for neural repair:

https://books.google.com/books?isbn=2889194027

Clare Parish, ‎Lachlan Thompson – 2015

While the link between electrical stimulation of the human brain and neurogenesis awaits investigation, a phase I clinical trial assessing the effect of DBS .

Targeted brain stimulation aids stroke recovery in mice, scientists find …

https://med.stanford.edu/…/targeted-brain-sti

Stanford University School of Medicine

Aug 18, 2014 – Animal studies have indicated that electrical stimulation of the brain can improve … However, “existing brain-stimulation techniques activate all cell types in the …. Neural stem cellshelped repair stroke damage in rats’ brains.

Less-invasive method of brain stimulation helps patients with …

https://www.sciencedaily.com/releases/2012/10/121016103413.htm

Science Daily

Oct 16, 2012 – Electrical stimulation using extradural electrodes—placed … meaningful benefits for patients with Parkinson’s disease, according to new research.

FDA approves the treatment of brain tumors with electrical fields

www.gizmag.com/treatment-of-braintumors-with-electrical-fields/21433/

Gizmag

Feb 13, 2012 – The promising new non-invasive treatment by Novocure uses “Tumor Treating Fields” (NovoTTF) to treat cancerous growths and is now …

Electrical Scalp Device Can Slow Progression of Deadly Brain Tumors …

www.nytimes.com/…/electrical-scalp-device-can-slow-progressi…

The New York Times

Nov 15, 2014 – An electrical device glued to the scalp can slow cancer growth and prolong … with the deadliest type of brain tumor, glioblastoma, researchers have found. … So far, Novocure has been providing it free to patients without …

Bill Doyle: Treating cancer with electric fields | TED Talk | TED.com

 15:35

https://www.ted.com/…/bill_doyle_treating_cancer_with_ele

TED

With his company Novocure, Bill Doyle works to bring breakthrough medical …. Please show me any 2 brain …

This Electric Helmet Looks Goofy But It Zaps Deadly Brain Cancer

gizmodo.com/this-electric-helmet-looks-goofy-but-it-zaps-deadly-bra-1579…

Gizmodo

May 22, 2014 – This Electric Helmet Looks Goofy But It Zaps Deadly Brain Cancer · Sarah Zhang … It Zaps Deadly Brain Cancer. Images courtesy of NovoCure.

Electroacupuncture preconditioning reduces cerebral ischemic injury …

bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-13-22

by JH Kim – ‎2013 – ‎Cited by 23 – ‎Related articles

In addition, we investigated whether the expression of brain-derived … The expression of BDNF proteinincreased significantly from 6 h, reaching a plateau at 12 h … Focal cerebral ischemia Electroacupuncture BDNF SDF-1α Preconditioning … of 1 mA and a frequency of 2 Hz for 20 min using Grass S88 electro stimulator …

STEM CELLS 

Breakthrough in stem cell treatment for Parkinson’s – Medical News …

www.medicalnewstoday.com/articles/285069.php

Medical News Today

 Rating: 4.7 – ‎10 votes

Nov 7, 2014 – Researchers say it is possible to make dopamine

Fetal cells injected into a man’s brain to cure his Parkinson’s | New …

https://www.newscientist.com/…/dn27593-fetal-cells-injected-into-a-man…

New Scientist

May 26, 2015 – An experimental Parkinson’s treatment abandoned in the 1990s has been … and couldrestore a person’s control of their movement

Cell replacement therapy for Parkinson’s disease – ScienceDirect

www.sciencedirect.com/science/article/pii/S0925443908001993

ScienceDirect

by R Wijeyekoon – ‎2009 – ‎Cited by 54 – ‎Related articles

Of these embryonic stem cells and induced pluripotent stem cells seem the most …. has always been attractive for the treatment of any disorder including Parkinson’s … This patient had derived some clinical benefit from the graft for ∼ 4 years … functional recovery following intra-striatal transplantation of carotid body cell …

Neural stem cell transplants aid traumatic brain injury recovery …

www.eurekalert.org/pub_releases/2016-04/ctco-nsc041916.php

Apr 19, 2016 – Traumatic brain injury (TBI) is a major cause of mortality and morbidity, often causing lifelong disability for those who survive. When researchers …

Stem cells help repair traumatic brain injury by building ‘biobridge …

https://www.sciencedaily.com/releases/2013/10/131003111204.htm

Science Daily

Oct 3, 2013 – Stem cells help repair traumatic brain injury by building ‘biobridge’ … in the brain in need of repair, helping promote functional recovery from …

Can Stem Cells Help Restore Brain Function After Traumatic Injury …

www.perkinelmer.com/…/can-stemcells-help-restore-brain-functionality-…

PerkinElmer

Nov 7, 2014 – Research using human neural stem cells (hNSCs) is showing promise. … stem cells(hNSCs) to promote recovery of neural function after injury.

Stem cell therapy shows promise in repairing brain damage even …

stemcellstm.alphamedpress.org/site/misc/PressRelease032.xhtml

Stem cell therapy shows promise in repairing brain damage even hours after stroke … ensure complete recovery for stroke patients poses an extreme challenge, …

Siddharthan Chandran: Can the damaged brain repair itself? – TED.com

 15:57

https://www.ted.com/…/siddharthan_chandran_can_the_dam

TED

Feb 24, 2014

After a traumatic brain injury, it sometimes happens that the brain can repairitself, building new brain cells …

Electrical stimulation of cerebellar fastigial nucleus promotes the …

www.sciencedirect.com/science/article/pii/S0304394012006908

ScienceDirect

by B Liu – ‎2012 – ‎Cited by 11 – ‎Related articles

This study focused on the effects of electrical stimulation of cerebellar fastigial nucleus on the expression of growth arrest and DNA damage inducible gene β.

These results suggest that FN electrical stimulation can promote the expression of Gadd45β and motor function recovery after focal cerebral ischemia.

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Sujet : Add to CerebraCell Related Articles on Web Site Page

Neuronal apoptosis in cerebral ischemia/reperfusion area following …

www.nrronline.org/article.asp?issn=1673

Neural Regeneration Research

by J Liu – ‎2014 – ‎Cited by 12 – ‎Related articles

May 29, 2014 – Results from the electrical stimulation group revealed that rats exhibited a …. TheDNA repair proteins, Ku70 and Ku80, are DNA-binding regulatory … Cytoplasmic Ku70 is involved in the control of cell apoptosis, specifically Bax-mediated apoptosis . …. Ku70 and Bax expressionfollowing fastigial nucleus

Neuronal apoptosis in cerebral ischemia/reperfusion area following …

www.nrronline.org/article.asp?issn=1673…

Neural Regeneration Research

by J Liu – ‎2014 – ‎Cited by 12 – ‎Related articles

May 29, 2014 – Results from the electrical stimulation group revealed that rats exhibited a …. TheDNA repair proteins, Ku70 and Ku80, are DNA-binding regulatory … Cytoplasmic Ku70 is involved in the control of cell apoptosis, specifically Bax-mediated apoptosis . …. Ku70 and Bax expressionfollowing fastigial nucleus

Biologists show bioelectrical signals control tumors arising from …

www.news-medical.net/…/Biologists-show-bioelectrical-signals-control-tumors-arising…

May 28, 2014 – “These distant bioelectric signals suppressed tumor growth, despite the cells’ … Prior News New fNIRS -FD instrument can identify affected areas of brain … Tecentriq drug gets FDA approval to treat urothelial carcinoma.

Electrical brain stimulation could support stroke recovery

medicalxpress.com › Neuroscience

Mar 16, 2016 – Applying an electric current to the brain can help recovery from … plus anodal tDCS compared to motor rehabilitation plus sham treatment.

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Electroacupuncture Treatment Improves Learning-Memory Ability – NCBI

www.ncbi.nlm.nih.gov/ 

 

National Center for Biotechnology Information

by J Jiang – ‎2015 – ‎Cited by 2 – ‎Related articles

Mar 3, 2015 – Electroacupuncture Treatment Improves Learning-Memory Ability and Brain Glucose Metabolism in a Mouse Model of Alzheimer’s Disease: …

Electroacupuncture Treatment Improves Learning … – ResearchGate

https://www.researchgate.net/…/274262088_Electroacupunctu  ResearchGate

Official Full-Text Publication: Electroacupuncture Treatment Improves Learning-Memory Ability and Brain Glucose Metabolism in a Mouse Model of Alzheimer’s …

New Alzheimer’s treatment fully restores memory function – ScienceAlert

https://www.sciencealert.com/new-alzheimer-s-treatment-fully-restores-m… 

Mar 18, 2015 – Of the mice that received the treatment, 75 percent got their memories back. … for Alzheimer’s – a disease that affects 343,000 people in Australia, and 50 … against bacteria, and stimulate the brain’s microglial cells to activate.

Acupuncture Rejuvenates Alzheimer’s Disease Patients – HealthCMi

www.healthcmi.com/…/1403-acupuncture-rejuvenates-alzheimer-s-diseas… 

Dec 8, 2014 – Electroacupuncture reduces brain plaque proliferation associated with Alzheimer’s disease and associated dementia. The researchers …

Therapeutic potential of neurogenesis for prevention and recovery …

www.ncbi.nlm.nih.gov/ 

 

National Center for Biotechnology Information

by RD Brinton – ‎2006 – ‎Cited by 100 – ‎Related articles

1. Curr Alzheimer Res. 2006 Jul;3(3):185-90. … neurogenesis for prevention and recovery from Alzheimer’s disease: allopregnanolone as … Brinton RD(1), Wang JM. … The discovery of neurogenesis in the adult brain and the regenerative … IGF1 and VEGF, in the microenvironment of the subgranular zone (SGZ) are prime ..

Higher Levels of IGF-1 Are Associated With a Decreased Risk of …

www.neurologyreviews.com/index.php?id=25318&tx_ttnews%5Btt 

Among a sample of participants from the Framingham study, high levels of IGF1 are linked to a lower risk of Alzheimer’sdisease and subclinical brain atrophy. SAN DIEGO—Dementia-free patients with high levels of insulin-like growth factor 1 (IGF1) show a lower risk of …

Alzheimer’s disease in men linked to low levels of hormone IGF-1 …

https://www.sciencedaily.com/releases/…/121002091759.ht 

 

Science Daily

Oct 2, 2012 – Low serum levels of insulin-like growth factor-1 (IGF1) and … Link Between Brain Insulin Resistance, Neuronal Stress in Worsening Alzheimer’s Disease. June 26 … Hormone Improves Long-Term Recovery from Stroke, Study …

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